Koraitim M M, Atta M A, Foda M K
Department of Urology, Faculty of Medicine, University of Alexandria, Egypt.
J Urol. 1995 Nov;154(5):1700-2; discussion 1702-3.
We studied the volume and pressure changes with time in detubularized and nondetubularized neobladders.
Cystometry was performed at early and late followup in 54 male patients with post-cystectomy intestinal neobladders constructed from an intact ileocecal segment in 33, detubularized sigmoid in 11 and detubularized ileum in 10.
With time the capacity of the neobladder increased in all 3 groups. Concomitantly, while intact ileocecal bladders showed an increase in intra-reservoir pressure and persistence of involuntary contractions, detubularized sigmoid and ileal bladders showed a decrease in intra-reservoir pressure and involuntary contractions.
Increased capacity with time is not due to detubularization per se but rather to over distension, which is more marked in detubularized (109 to 112%) than in tubular (79%) segments. Detubularized intestinal neobladders not only offer a high capacity, low pressure and high compliant reservoir but these characteristics also are increased with time.
我们研究了去管化和未去管化新膀胱的容量和压力随时间的变化。
对54例膀胱切除术后采用完整回盲肠段构建新膀胱的男性患者（33例）、去管化乙状结肠构建新膀胱的男性患者（11例）以及去管化回肠构建新膀胱的男性患者（10例）进行了早期和晚期随访膀胱测压。
随着时间推移，所有3组新膀胱的容量均增加。同时，完整回盲肠膀胱的储尿囊内压升高且存在不自主收缩，而去管化乙状结肠和回肠膀胱的储尿囊内压及不自主收缩减少。
容量随时间增加并非源于去管化本身，而是由于过度扩张，去管化节段（109%至112%）的过度扩张比管状节段（79%）更明显。去管化肠新膀胱不仅提供高容量、低压和高顺应性的储尿囊，而且这些特性还会随时间增加。
