Yasuda T, Ushijima T, Kawasuji M, Watanabe Y
Department of Surgery I, Kanazawa University School of Medicine, Japan.
Kyobu Geka. 1995 Oct;48(11):915-8.
Continuous infusion of warm blood cardioplegic solution is often interrupted during coronary artery bypass grafting to obtain a bloodless operating field. We measured myocardial oxygen saturation continuously using near-infrared spectroscopy to determine myocardial oxygen metabolism during intermittent warm blood cardioplegia (IWBC). In 7 adult mongrel dogs undergoing cardiopulmonary bypass IWBC was administered using the Buckberg-Shiley system. Cardiac arrest was induced by a warm blood cardioplegic infusion of 100 ml/min for 5 minutes followed by a maintenance infusion of 40 ml/min for 5 minutes. The infusion of warm blood cardioplegia was then stopped for 15 minutes. Measurement of myocardial oxygen saturation was performed continuously throughout cardiopulmonary bypass. IWBC produced an increase in myocardial oxygen saturation for the first 5 minutes and a slight decrease for the second 5 minutes. After the termination of IWBC, myocardial oxygen saturation showed a marked reduction for 3 minutes and plateaued after 5 minutes. Measurement of myocardial oxygen saturation revealed myocardial oxygen metabolism during IWBC. This procedure may be a useful way to monitor myocardial oxygen metabolism during open heart surgery.
在冠状动脉搭桥手术期间,持续输注温血心脏停搏液常常会被中断,以获得无血的手术视野。我们使用近红外光谱法连续测量心肌氧饱和度,以确定间歇性温血心脏停搏(IWBC)期间的心肌氧代谢。在7只接受体外循环的成年杂种犬中,使用Buckberg-Shiley系统进行IWBC。通过以100 ml/min的速度输注温血心脏停搏液5分钟诱导心脏停搏,随后以40 ml/min的速度维持输注5分钟。然后停止输注温血心脏停搏液15分钟。在整个体外循环过程中持续测量心肌氧饱和度。IWBC在最初5分钟使心肌氧饱和度增加,在第二个5分钟略有下降。IWBC终止后,心肌氧饱和度在3分钟内显著降低,并在5分钟后趋于平稳。心肌氧饱和度的测量揭示了IWBC期间的心肌氧代谢。该方法可能是一种在心脏直视手术期间监测心肌氧代谢的有用方法。