Yasuda T, Sawa S, Ishikawa N, Tanaka N
Department of Thoracic and Cardiovascular Surgery, Yokohama Sakae Kyosai Hospital, Yokohama.
Ann Thorac Cardiovasc Surg. 1998 Oct;4(5):271-4.
Simultaneous measurement of coronary venous oxygen saturation and coronary venous blood flow is an essential method that reveals myocardial oxygen metabolism. But there have been no reports of the simultaneous measurements during warm blood cardioplegic infusion in cardiac surgery. Thirteen patients underwent elective coronary artery bypass grafting in our unit. Simultaneous measurement of coronary venous oxygen saturation (ScsO2) and coronary venous blood flow (Fcs) was carried out during terminal warm blood cardioplegia. Fcs increased rapidly and reached plateau level (178 +/- 18 ml/min) between 0 and 1 min after blood cardioplegic infusion. But ScsO2 increased slowly and reached a peak level (84 +/- 3%) between 1 and 2 min after blood cardioplegic infusion, and then dropped gradually. Using the Fick formula, myocardial oxygen consumption at 5 min after blood cardioplegic infusion was 3.7 ml/min/heart. Simultaneous continuous measurements of ScsO2 and Fcs were useful monitors of the myocardial distribution of the blood cardioplegic solution, and cleared the myocardial oxygen metabolism during terminal warm blood cardioplegia.
同时测量冠状静脉血氧饱和度和冠状静脉血流量是揭示心肌氧代谢的重要方法。但在心脏手术中温血心脏停搏液输注期间进行同步测量尚无报道。我们单位有13例患者接受了择期冠状动脉旁路移植术。在终末温血心脏停搏期间同时测量冠状静脉血氧饱和度(ScsO2)和冠状静脉血流量(Fcs)。Fcs在血液心脏停搏液输注后0至1分钟内迅速增加并达到平台期水平(178±18毫升/分钟)。但ScsO2上升缓慢,在血液心脏停搏液输注后1至2分钟内达到峰值水平(84±3%),然后逐渐下降。使用Fick公式,血液心脏停搏液输注后5分钟时心肌耗氧量为3.7毫升/分钟/心脏。同时连续测量ScsO2和Fcs是监测血液心脏停搏液在心肌中分布情况的有用手段,并明确了终末温血心脏停搏期间的心肌氧代谢。