Charny C K, Jacobowitz G, Melamed J, Tata M, Harris M N
Department of Surgery, New York University School of Medicine, New York 10016, USA.
J Surg Oncol. 1995 Oct;60(2):128-30. doi: 10.1002/jso.2930600212.
Malignant melanoma metastases to regional lymph nodes may be mimicked by several non-neoplastic processes, including sinus histiocytosis induced by fragments shed from joint prostheses. A patient who had an elective lymph node dissection for malignant melanoma and was found to have "post-prosthesis lymph node histiocytosis" resembling metastatic disease is described. Knowledge of the patient's past history of a total shoulder joint replacement along with the use of polarized light microscopy to identify birefringent particles of prosthetic debris allows for an accurate histologic diagnosis.
恶性黑色素瘤转移至区域淋巴结可能被几种非肿瘤性病变所模拟，包括关节假体碎片引发的窦性组织细胞增多症。本文描述了一名因恶性黑色素瘤接受择期淋巴结清扫术的患者，其被发现存在类似转移性疾病的“假体后淋巴结组织细胞增多症”。了解患者既往全肩关节置换病史，并利用偏振光显微镜识别假体碎片的双折射颗粒，有助于做出准确的组织学诊断。
