Winstanley A M, Sandison A, Bott S R J, Dogan A, Parkinson M C
Department of Histopathology, North Midllesex Hospital, UCL Hospitals NHS Trust, London WC1E 6JJ,
J Clin Pathol. 2002 Aug;55(8):623-6. doi: 10.1136/jcp.55.8.623.
To assess the frequency and cause of incidental (non-metastatic) lymph node pathology discovered before or at radical prostatectomy.
Eight hundred and fifty four consecutive lymphadenectomies received between 1988 and 2001 were reviewed. All had been processed and stained routinely. Additional techniques, indicated by morphology, were then performed.
Incidental pathology was found in 15 cases: florid sinus histiocytosis following prosthetic joint replacement (eight), non-caseating granulomas (three), small lymphocytic cell lymphoma (two), follicular lymphoma (one), and foreign body reaction (one). Incidental pathology was present in 1.8% of 854 patients who underwent pelvic lymphadenectomy during radical prostatectomy.
Awareness of possible non-metastatic lymph node pathology aids histological diagnosis and may be clinically relevant.
评估在根治性前列腺切除术之前或术中发现的偶然(非转移性)淋巴结病变的频率及原因。
回顾了1988年至2001年间连续进行的854例淋巴结切除术。所有标本均进行了常规处理和染色。然后根据形态学表现进行了额外的技术操作。
15例发现偶然病变:人工关节置换术后的弥漫性窦组织细胞增生症(8例)、非干酪样肉芽肿(3例)、小淋巴细胞性淋巴瘤(2例)、滤泡性淋巴瘤(1例)和异物反应(1例)。在854例行根治性前列腺切除术时接受盆腔淋巴结清扫术的患者中,偶然病变的发生率为1.8%。
认识到可能存在的非转移性淋巴结病变有助于组织学诊断,且可能具有临床意义。