Guay M E, Miller F R, Bauer T W, Tucker H M
Department of Otolaryngology and Communicative Disorders, Cleveland Clinic Foundation, OH 44195, USA.
Laryngoscope. 1995 Oct;105(10):1049-52. doi: 10.1288/00005537-199510000-00007.
Unilateral vocal fold paralysis can alter phonation. Medialization of the vocal fold using cartilage augmentation dates to the early 1950s. Improved phonation after cartilage chordal augmentation has been reported, but no study has as yet documented cartilage viability or size in this setting over time. The authors of this study evaluated thyroid alar cartilage as a medializing material in three mongrel dogs. Grafts were inserted lateral to the inner thyroid perichondrium at the vocal fold level via a window in the thyroid cartilage. Changes in weight, size, and volume were assessed 6 months after implantation. The average graft weight declined by 15%, and the average square area declined by 3%. Importantly, the average volume maintained was 87%. The grafts remained rigidly fixed to the thyroid cartilage in their placement positions. Histologic examination documented minimal resorption. The data suggest that thyroid alar cartilage is a viable filler in type I thyroplasty procedures.
单侧声带麻痹会改变发声。使用软骨增大术使声带内移可追溯到20世纪50年代早期。已有报道称软骨弦状增大术后发声得到改善，但尚无研究记录在此情况下软骨随时间推移的活力或大小。本研究的作者在三只杂种犬中评估了甲状软骨翼作为一种使声带内移的材料。通过甲状软骨上的一个窗口，将移植物植入声带水平甲状软骨内侧软骨膜外侧。植入6个月后评估移植物的重量、大小和体积变化。移植物平均重量下降了15%，平均面积下降了3%。重要的是，平均保留体积为87%。移植物在其植入位置牢固地固定在甲状软骨上。组织学检查显示吸收极少。数据表明甲状软骨翼是I型甲状成形术可行的填充物。
