Stafford T J, Lizek R, Tan O T
Tufts University, Boston, Massachusetts 02116, USA.
Lasers Surg Med. 1995;17(1):32-8. doi: 10.1002/lsm.1900170104.
The development of the Alexandrite laser for the removal of blue-black tattoos is described.
STUDY DESIGN/MATERIALS AND METHODS: The responses of an animal study, using professionally tattooed skin and a human study involving 22 (professional and nonprofessional) blue-black tattoos, to the Alexandrite laser are reported.
Histopathologic evaluation of tattooed pig skin biopsies demonstrated the method of removal of dermal tattoo pigment. An average 11.6 treatments were required to remove completely the ten human blue-black professional tattoos compared to an average of 10.3 treatments to reach the same endpoint in six subjects with nonprofessional tattoos.
Of significance was the fact that unlike the Q-switched Ruby and Nd:YAG lasers where punctate bleeding and tissue splattering have been reported to occur during laser tattoo removal, epidermal integrity was maintained during exposure of tattooed skin to the Q-switched Alexandrite laser at therapeutic fluences used.
描述了用于去除蓝黑色纹身的翠绿宝石激光的发展历程。
研究设计/材料与方法：报告了一项动物研究（使用专业纹身皮肤）和一项涉及22处（专业和非专业）蓝黑色纹身的人体研究对翠绿宝石激光的反应。
对纹身猪皮肤活检标本的组织病理学评估显示了去除真皮纹身色素的方法。完全去除10处人类专业蓝黑色纹身平均需要11.6次治疗，而6名有非专业纹身的受试者达到相同终点平均需要10.3次治疗。
重要的是，与调Q红宝石激光和Nd:YAG激光不同，据报道在激光纹身去除过程中会出现点状出血和组织飞溅，而在使用治疗剂量的调Q翠绿宝石激光照射纹身皮肤时，表皮完整性得以保持。
