Zelickson B D, Mehregan D A, Zarrin A A, Coles C, Hartwig P, Olson S, Leaf-Davis J
Department of Dermatology, University of Minnesota Medical School, Minneapolis 55455.
Lasers Surg Med. 1994;15(4):364-72. doi: 10.1002/lsm.1900150406.
We examined the response of tattoo pigments treated with three commercially available lasers: Q-switched ruby, Q-Switched neodynium:yttrium,aluminum,garnet (Nd:YAG), and the alexandrite. Tattoos applied to hairless guinea pigs and treated with the aforementioned lasers were evaluated clinically, histologically, and ultrastructurally. Clinical evaluation showed red brown, dark brown, and orange pigment responded best to the Nd:YAG laser (1064 nm). The alexandrite laser was most effective for removing blue and green pigment, the Q-switched ruby laser was most effective for removing purple and violet pigment, and the Nd:YAG laser (532 nm) removed red pigment the best. Black pigment was lightened equally with the Nd:YAG laser (1064 nm) and (532 nm) and the alexandrite laser (755 nm). No clinical scarring was observed; however, some colors turned black after treatment. Histologic and ultrastructural examination showed epidermal and dermal damage to be most evident after treatment with the Nd:YAG laser. Our study shows that certain tattoo pigments respond better to different laser systems.
调Q红宝石激光、调Q钕：钇铝石榴石（Nd:YAG）激光和翠绿宝石激光。对应用于无毛豚鼠身上的纹身，用上述激光进行处理后，从临床、组织学和超微结构方面进行了评估。临床评估显示，红棕色、深棕色和橙色颜料对Nd:YAG激光（1064纳米）反应最佳。翠绿宝石激光对去除蓝色和绿色颜料最有效，调Q红宝石激光对去除紫色和紫罗兰色颜料最有效，Nd:YAG激光（532纳米）去除红色颜料效果最佳。黑色颜料用Nd:YAG激光（1064纳米）、（532纳米）和翠绿宝石激光（755纳米）处理后变淡程度相同。未观察到临床瘢痕形成；然而，有些颜色在治疗后变黑。组织学和超微结构检查显示，用Nd:YAG激光治疗后，表皮和真皮损伤最为明显。我们的研究表明，某些纹身颜料对不同的激光系统反应更佳。
