Idiopathic haemochromatosis: magnetic resonance signal intensity ratios permit non-invasive diagnosis of low levels of iron overload.
作者信息
Macfarlane J D, Vreugdenhil G R, Doornbos J, van der Voet G B
机构信息
Department of Rheumatology, University Hospital, Leiden, Netherlands.
出版信息
Neth J Med. 1995 Aug;47(2):49-53. doi: 10.1016/0300-2977(95)00038-o.
OBJECTIVE
The detection of low levels of iron overload by magnetic resonance imaging.
METHODS
Eight consecutive patients suspected of having idiopathic haemochromatosis. Comparison of signal intensity ratios and absolute iron content of liver.
RESULTS
There was a good correlation between the signal intensity ratios and iron content in the range 2-30 micrograms Fe/mg dry weight.
CONCLUSIONS
The ability of a non-invasive technique to detect low levels of iron overload could be useful in the assessment of therapy and in the screening of relatives of probands with idiopathic haemochromatosis.
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