Nzeyimana H, Jaber W, Beaufils H, Goldstein A, Babinet F, Kernaonet E, Lebon P
Service de néphrologie-dialyse, Centre hospitalier général, Le Mans.
Nephrologie. 1995;16(5):377-80.
Occurrence of crescentic formation superimposed to idiopathic membranous glomerulopathy worsens severely its prognosis with evolution to end stage renal disease. We report the case of a 65 years old man with nephrotic idiopathic membranous glomerulopathy who subsequently developed an acute renal failure secondary to crescentic formation. Pulse of high dose methylprednisolone administration improved renal function. Seven similar observations are analysed and pathogenic mechanisms discussed.
特发性膜性肾小球病叠加新月体形成会严重恶化其预后,并进展至终末期肾病。我们报告了一例65岁患有肾病性特发性膜性肾小球病的男性患者,其随后因新月体形成继发急性肾衰竭。大剂量甲基强的松龙冲击治疗改善了肾功能。分析了另外7例类似病例并讨论了发病机制。