Bizet C, Bizet J
Institut Pasteur, Paris, France.
Pathol Biol (Paris). 1995 Apr;43(4):258-63.
Ochrobactrum anthropi, formerly known as "Achromobacter sp." or CDC group Vd has been isolated from water, hospital environment (antiseptic solutions, dialysis fluids ... ). O. anthropi is a Gram negative, motile, strictly aerobic, oxydase positive and non-fermentative bacteria with a strong urease activity. The susceptibility of 13 strains of O. anthropi was determined by agar diffusion method and compared to those of type strains of Agrobacterium tumefaciens, Alcaligenes faecalis, Alcaligenes denitrificans subsp. denitrificans, Alcaligenes denitrificans subsp. xylosoxydans and Bordetella bronchiseptica. The MICs of 20 antimicrobial agents confirmed the distinct phenotype susceptibility of O. anthropi. All the strains of O. anthropi are sensitive to imipenem, amikacin, gentamicin, netilmicin, nalidixic acid, pefloxacin, ciprofloxacin, tetracyclin, colistin, sulphonamides and rifampicin and resistant to ampicillin, amoxycillin + clavulanic acid, ticarcillin, mezlocillin, cefuroxime, cefamandol, cefoxitin, cefotaxime, cefoperazon, ceftazidime, cefsulodin, aztreonam, streptomycin, kanamycin, pipemidic acid, chloramphenicol, erythromicin, pristinamycin, trimethoprim and fosfomycin. O. anthropi is implicated in nosocomial infections. O. anthropi was the species with the greatest resistance to beta-lactamins.
嗜水气单胞菌，以前称为“Achromobacter sp.”或CDC Vd组，已从水、医院环境（防腐剂溶液、透析液等）中分离出来。嗜水气单胞菌是一种革兰氏阴性、运动性、严格需氧、氧化酶阳性且非发酵的细菌，具有很强的脲酶活性。通过琼脂扩散法测定了13株嗜水气单胞菌的药敏性，并与根癌土壤杆菌、粪产碱菌、反硝化产碱菌反硝化亚种、反硝化产碱菌木糖氧化亚种和支气管败血波氏杆菌的模式菌株进行了比较。20种抗菌药物的最低抑菌浓度证实了嗜水气单胞菌独特的表型药敏性。所有嗜水气单胞菌菌株对亚胺培南、阿米卡星、庆大霉素、奈替米星、萘啶酸、培氟沙星、环丙沙星、四环素、黏菌素、磺胺类药物和利福平敏感，对氨苄西林、阿莫西林+克拉维酸、替卡西林、美洛西林、头孢呋辛、头孢孟多、头孢西丁、头孢噻肟、头孢哌酮、头孢他啶、头孢磺啶、氨曲南、链霉素、卡那霉素、吡哌酸、氯霉素、红霉素、 pristinamycin、甲氧苄啶和磷霉素耐药。嗜水气单胞菌与医院感染有关。嗜水气单胞菌是对β-内酰胺类耐药性最强的菌种。
