Zupancic Z, Primozic J
Department of Radiology, University Medical Center Ljubljana, Zaloska, Slovenia.
Pediatr Radiol. 1995;25(5):332-6. doi: 10.1007/BF02021695.
Tracheobronchomegaly (TBM) was diagnosed on chest radiographs as an apparent dilatation of the trachea and main bronchi in four premature infants on prolonged mechanical ventilation for respiratory distress syndrome. In a retrospective study, the parameters of assisted ventilation, the Apgar score, the presence of conatal or later infection, and hypotension were reviewed and analyzed as factors possibly contributing to the pathogenesis of TBM in these infants. The results lead to the conclusion that TBM in premature infants on prolonged ventilatory support is an acquired condition though a congenital defect cannot be excluded as a probable predisposing factor. In the etiopathogenesis of TBM, a repeated barotrauma of prolonged ventilation is a crucial factor while the severity of lung disease and the degree of prematurity, hypotension, infection, and generally poor clinical condition, all appear to be relevant in the development of TBM in a premature infant with respiratory distress syndrome.
在胸部X线片上，4例因呼吸窘迫综合征接受长时间机械通气的早产儿被诊断为气管支气管巨大症（TBM），表现为气管和主支气管明显扩张。在一项回顾性研究中，对辅助通气参数、阿氏评分、先天性或后天性感染的存在情况以及低血压进行了审查和分析，将其作为可能导致这些婴儿发生TBM的因素。结果得出结论，接受长时间通气支持的早产儿发生的TBM是一种后天获得性疾病，尽管不能排除先天性缺陷作为可能的易感因素。在TBM的病因发病机制中，长时间通气导致的反复气压伤是一个关键因素，而肺部疾病的严重程度、早产程度、低血压、感染以及总体较差的临床状况，似乎都与患有呼吸窘迫综合征的早产儿发生TBM有关。
