The nascent-polypeptide-associated complex: having a "NAC" for fidelity in translocation.
作者信息
Wickner W
机构信息
Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755-3844, USA.
出版信息
Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9433-4. doi: 10.1073/pnas.92.21.9433.
Abstract
摘要
相似文献
1
The nascent-polypeptide-associated complex: having a "NAC" for fidelity in translocation.新生多肽相关复合体：在转运过程中保持忠实性的“NAC”。
Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9433-4. doi: 10.1073/pnas.92.21.9433.
2
The intrinsic ability of ribosomes to bind to endoplasmic reticulum membranes is regulated by signal recognition particle and nascent-polypeptide-associated complex.核糖体与内质网膜结合的内在能力受信号识别颗粒和新生多肽相关复合物的调节。
Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9435-9. doi: 10.1073/pnas.92.21.9435.
3
Nascent-polypeptide-associated complex: a bridge between ribosome and cytosol.
Cold Spring Harb Symp Quant Biol. 1995;60:47-56. doi: 10.1101/sqb.1995.060.01.008.
4
Nascent-polypeptide-associated complex.新生多肽相关复合体
Cell Mol Life Sci. 2002 Oct;59(10):1632-9. doi: 10.1007/pl00012490.
5
The environment of nascent secretory and membrane proteins at the endoplasmic reticulum membrane during translocation and integration.
Cold Spring Harb Symp Quant Biol. 1995;60:71-82. doi: 10.1101/sqb.1995.060.01.010.
6
Unregulated exposure of the ribosomal M-site caused by NAC depletion results in delivery of non-secretory polypeptides to the Sec61 complex.NAC耗竭导致核糖体M位点的无调控暴露，从而使非分泌性多肽被递送至Sec61复合体。
FEBS Lett. 1998 Dec 11;441(1):1-5. doi: 10.1016/s0014-5793(98)01440-9.
7
A protein complex required for signal-sequence-specific sorting and translocation.一种信号序列特异性分选和转运所需的蛋白质复合物。
Nature. 1994 Aug 11;370(6489):434-40. doi: 10.1038/370434a0.
8
A general mechanism for regulation of access to the translocon: competition for a membrane attachment site on ribosomes.一种调控进入转位子的通用机制：核糖体上膜附着位点的竞争。
Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13425-30. doi: 10.1073/pnas.95.23.13425.
9
The alpha and beta subunit of the nascent polypeptide-associated complex have distinct functions.新生多肽相关复合体的α亚基和β亚基具有不同的功能。
J Biol Chem. 2000 Dec 1;275(48):37838-45. doi: 10.1074/jbc.M006368200.
10
Elongation arrest is a physiologically important function of signal recognition particle.延伸阻滞是信号识别颗粒的一种重要生理功能。
EMBO J. 2000 Aug 1;19(15):4164-74. doi: 10.1093/emboj/19.15.4164.
引用本文的文献
1
Biophysical and Biochemical Characterization of Nascent Polypeptide-Associated Complex of and Elucidation of Its Interacting Partners.新生多肽相关复合物的生物物理和生化特性及其相互作用伙伴的阐明
Front Microbiol. 2020 May 26;11:915. doi: 10.3389/fmicb.2020.00915. eCollection 2020.
2
Fidelity of cotranslational protein targeting by the signal recognition particle.信号识别颗粒对共翻译蛋白靶向的保真度。
Annu Rev Biophys. 2014;43:381-408. doi: 10.1146/annurev-biophys-051013-022653.
3
Translation elongation regulates substrate selection by the signal recognition particle.翻译延伸调控信号识别颗粒对底物的选择。
J Biol Chem. 2012 Mar 2;287(10):7652-60. doi: 10.1074/jbc.M111.325001. Epub 2012 Jan 6.
4
Signal recognition particle-dependent targeting of ribosomes to the rough endoplasmic reticulum in the absence and presence of the nascent polypeptide-associated complex.在有无新生多肽相关复合物的情况下，信号识别颗粒介导核糖体靶向粗面内质网。
Mol Biol Cell. 1998 Jan;9(1):117-30. doi: 10.1091/mbc.9.1.117.
5
Ribosome regulation by the nascent peptide.新生肽对核糖体的调控
Microbiol Rev. 1996 Jun;60(2):366-85. doi: 10.1128/mr.60.2.366-385.1996.
本文引用的文献
1
GTP hydrolysis by complexes of the signal recognition particle and the signal recognition particle receptor.信号识别颗粒与信号识别颗粒受体的复合物对鸟苷三磷酸（GTP）的水解作用
J Cell Biol. 1993 Nov;123(4):799-807. doi: 10.1083/jcb.123.4.799.
2
An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY.大肠杆菌中的另一种蛋白质靶向途径：FtsY作用的研究
EMBO J. 1994 May 15;13(10):2289-96. doi: 10.1002/j.1460-2075.1994.tb06511.x.
3
Interaction of E. coli Ffh/4.5S ribonucleoprotein and FtsY mimics that of mammalian signal recognition particle and its receptor.大肠杆菌Ffh/4.5S核糖核蛋白与FtsY的相互作用模拟了哺乳动物信号识别颗粒及其受体的相互作用。
Nature. 1994 Feb 17;367(6464):657-9. doi: 10.1038/367657a0.
4
Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex.核糖体与由Sec61p复合体介导的糙面内质网的结合。
J Cell Biol. 1994 Aug;126(4):925-34. doi: 10.1083/jcb.126.4.925.
5
A protein complex required for signal-sequence-specific sorting and translocation.一种信号序列特异性分选和转运所需的蛋白质复合物。
Nature. 1994 Aug 11;370(6489):434-40. doi: 10.1038/370434a0.
6
Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.酿酒酵母信号识别颗粒功能表达所需的亚基。
EMBO J. 1994 Sep 15;13(18):4390-400. doi: 10.1002/j.1460-2075.1994.tb06759.x.
7
Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum.新生多肽相关复合体蛋白可防止新生肽链错误靶向内质网。
Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5411-5. doi: 10.1073/pnas.92.12.5411.
8
The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer.内质网膜中的蛋白质传导通道向脂质双层横向开放。
Cell. 1995 Apr 21;81(2):207-14. doi: 10.1016/0092-8674(95)90330-5.
9
A chloroplast homologue of the signal recognition particle subunit SRP54 is involved in the posttranslational integration of a protein into thylakoid membranes.信号识别颗粒亚基SRP54的叶绿体同源物参与蛋白质向类囊体膜的翻译后整合。
Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3789-93. doi: 10.1073/pnas.92.9.3789.
10
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane.内质网膜中的靶向后信号序列识别事件。
Cell. 1995 Jul 28;82(2):261-70. doi: 10.1016/0092-8674(95)90313-5.
Zotero 插件