Wolfersdorf M, Keller F, Maier V, Fröscher W, Kaschka W P
Weissenau State Mental Hospital, Department of Psychiatry, Germany.
Pharmacopsychiatry. 1995 May;28(3):77-9. doi: 10.1055/s-2007-979594.
There has been some discussion in the recent literature regarding the possible relationship between peripheral levels of folate and serotonin deficiency in the CNS. At the same time, such a serotonin deficiency has been implicated in the biology of suicidal behavior. Thus, decreased peripheral folate levels may be expected in patients who commit violent suicide. In this study, the red-cell and serum folate levels in nine persons who later committed suicide are compared with those in age- and sex-matched control groups. A one-way analysis of variance showed no significant difference between the groups.
