Loza B
Katedra i Klinika Psychiatrii AM w Lublinie.
Psychiatr Pol. 1995 Jul-Aug;29(4):529-38.
A minority of patients treated with serotonergic agents develop a fulminant and potentially life-threatening illness characterized by changes in mental status, restlessness, myoclonus, hyperreflexia, tremor, shivering, incoordination, hyperthermia, diaphoresis and diarrhea. This condition of serotonergic hyperstimulation is called the "serotonin syndrome". The author describes an adverse response in a patient given fluoxetine and lithium. A 61-year-old woman presented to casualty exhibits nearly all of the diagnostic criteria proposed by Sternbach [17].
少数接受血清素能药物治疗的患者会患上一种暴发性且可能危及生命的疾病,其特征为精神状态改变、烦躁不安、肌阵挛、反射亢进、震颤、寒战、共济失调、体温过高、多汗和腹泻。这种血清素能过度刺激的状况被称为“血清素综合征”。作者描述了一名服用氟西汀和锂的患者的不良反应。一名61岁女性到急诊就诊,几乎呈现出斯特恩巴赫[17]提出的所有诊断标准。