磁共振成像中用于侧脑室容积测量的体视学和分割技术比较

A comparison of stereology and segmentation techniques for volumetric measurements of lateral ventricles in magnetic resonance imaging.

作者信息

Keshavan M S, Anderson S, Beckwith C, Nash K, Pettegrew J W, Krishnan K R

机构信息

Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, PA 15213-2593, USA.

出版信息

Psychiatry Res. 1995 May 31;61(1):53-60. doi: 10.1016/0925-4927(95)02446-5.

DOI:10.1016/0925-4927(95)02446-5

PMID:7568569

Abstract

Lateral ventricular volumes were measured on magnetic resonance imaging (MRI) scans by independent raters in 18 subjects (11 psychotic patients and 7 healthy control subjects) with two different approaches: a point-counting stereological (PCS) technique and a computerized technique based on segmentation algorithms. The correlation between the two techniques was very high (r = 0.96), and phantom studies showed good validity for both approaches. These findings and the technical simplicity of the PCS technique support its potential use for MRI morphometric measurements.

摘要

18名受试者（11名精神病患者和7名健康对照者）的侧脑室容积通过磁共振成像（MRI）扫描，由独立评估者采用两种不同方法进行测量：一种是点计数体视学（PCS）技术，另一种是基于分割算法的计算机化技术。两种技术之间的相关性非常高（r = 0.96），模型研究表明两种方法都具有良好的有效性。这些发现以及PCS技术的技术简便性支持了其在MRI形态测量中的潜在应用。