Jinkins J R, Rauch R A, Gee G T, Bazan C, Xiong L, Kashanian F K, Hanna E P
Department of Radiology, University of Texas Health Science Center, San Antonio 78240-7800, USA.
Radiology. 1995 Oct;197(1):247-51. doi: 10.1148/radiology.197.1.7568831.
To determine normal magnetic resonance (MR) imaging enhancement characteristics of the lumbosacral spine after intravenous administration of an expanded dose of gadopentetate dimeglumine.
T1-weighted MR images of the lumbosacral spine were acquired before and after injection of 0.3 mmol/kg gadopentetate dimeglumine in 12 healthy subjects (eight men, four women; age range, 22-57 years).
In 10 (91%) of the 11 subjects who completed the investigation, multifocal linear enhancement within the thecal sac that generally extended from the conus to the nerve-root sheaths was demonstrated. In all cases, enhancement was seen in the facet joints and the intervertebral disks parallel to the vertebral end-plates.
After an expanded dose of intravenous gadopentetate dimeglumine, multiple intrathecal and extrathecal structures were enhanced. Recognition of normal enhancement patterns after an expanded gadopentetate dimeglumine dose is important because such enhancement after routine injection of 0.1 mmol/kg gadopentetate dimeglumine is often thought to indicate disease.
确定静脉注射大剂量钆喷酸葡胺后腰骶椎的正常磁共振（MR）成像增强特征。
对12名健康受试者（8名男性，4名女性；年龄范围22 - 57岁）在注射0.3 mmol/kg钆喷酸葡胺前后采集腰骶椎的T1加权MR图像。
在完成研究的11名受试者中的10名（91%）中，显示出蛛网膜下腔内多灶性线性强化，通常从圆锥延伸至神经根鞘。在所有病例中，小关节和与椎体终板平行的椎间盘均可见强化。
静脉注射大剂量钆喷酸葡胺后，多个鞘内和鞘外结构出现强化。认识到大剂量钆喷酸葡胺后的正常强化模式很重要，因为常规注射0.1 mmol/kg钆喷酸葡胺后的这种强化常被认为提示疾病。
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