Revenga Arranz F, de Argila Fernández-Durán D, Rivera Díaz R, Iglesias Díez L
Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid.
Rev Clin Esp. 1995 Aug;195(8):550-2.
Lichen planus is an inflammatory dermatosis that has been associated to different chronic hepatopaties with a variable frequency. In recent years several case reports have been published dealing with lichen planus and its association to hepatitis C virus infection. We report six patients with lichen planus (four males, two females; aged 30-75) who also suffered a chronic hepatitis C virus infection. Lichen planus was confirmed by biopsy and viral infection was based on ELISA and RIBA-4 tests in all patients and also on PCR in five of them. A patient had also been diagnosed of porphyria cutanea tarda. Two patients were treated with alfa-Interferon. It did not modify the evolution of their lichen planus. We recommend to search for hepatitis C virus infection in lichen planus patients and also look for lichen planus patients suffering of chronic hepatopathies to improve our knowledge of the possible relation between both diseases.
扁平苔藓是一种炎症性皮肤病，其与不同的慢性肝病的关联频率各不相同。近年来，已发表了几例关于扁平苔藓及其与丙型肝炎病毒感染关联的病例报告。我们报告了6例扁平苔藓患者（4例男性，2例女性；年龄30 - 75岁），他们同时患有慢性丙型肝炎病毒感染。所有患者均通过活检确诊为扁平苔藓，病毒感染通过ELISA和RIBA - 4检测确定，其中5例还进行了PCR检测。1例患者还被诊断为迟发性皮肤卟啉病。2例患者接受了α - 干扰素治疗。这并未改变他们扁平苔藓的病程。我们建议对扁平苔藓患者进行丙型肝炎病毒感染筛查，同时也应寻找患有慢性肝病的扁平苔藓患者，以增进我们对这两种疾病可能关系的了解。
