Martrenchar A, Bouchel D, Njanpop B M, Yaya A
Laboratoire national vétérinaire de Boklé, Garoua, Cameroun.
Rev Elev Med Vet Pays Trop. 1995;48(1):37-40.
Four herds of zebus from northern Cameroon totalling 136 animals were vaccinated subcutaneously with the following doses of Brucella abortus strain 19: 5 x 10(9) colony-forming units (CFU), 10(9) CFU, 5 x 10(8) CFU and 10(7) CFU. Twenty-eight days after vaccination, the following seroconversion rates were observed respectively: 97.4, 96.2 84.2 and 73.3%. Of the 52 animals which could be tested subsequently including 39 over one year old on the vaccination day, only one showed antibodies 6 months after vaccination. The cost price of the strain 19 vaccine produced at the Boklé National Veterinary Laboratory was estimated to be 65 F CFA at the 10(9) CFU dose and 1,740 F CFA at the 5 x 10(10) CFU dose usually recommended. The use of the Buck 19 strain in the medical prophylaxis of bovine brucellosis in northern Cameroon is discussed.
来自喀麦隆北部的四群泽布牛，共136头，分别皮下接种了以下剂量的布鲁氏菌流产菌株19：5×10⁹菌落形成单位（CFU）、10⁹CFU、5×10⁸CFU和10⁷CFU。接种疫苗28天后，观察到的血清转化率分别为：97.4%、96.2%、84.2%和73.3%。在随后可以检测的52头牛中，包括接种疫苗当天39头一岁以上的牛，接种疫苗6个月后只有一头显示有抗体。博克莱国家兽医实验室生产的19菌株疫苗的成本价估计为：10⁹CFU剂量时为65非洲金融共同体法郎，通常推荐的5×10¹⁰CFU剂量时为1740非洲金融共同体法郎。讨论了在喀麦隆北部牛布鲁氏菌病的医学预防中使用19菌株的情况。
