Aucella F, Martini E, Centra M, Di Tullio M, Di Giorgio G, Stallone C
Divisione di Nefrologia e Dialisi, Ospedale Casa Sollievo della Sofferenza IRCCS, San Giovanni Rotondo, Foggia.
Recenti Prog Med. 1995 Sep;86(9):332-5.
In order to evaluate epidemiological features of hepatitis C virus infection in patients with chronic renal failure, we enrolled 80 haemodialyzed subjects in four centers of Gargano area (Southern Italy). In a 28 months follow-up we checked antiHCV antibodies by EIA II and viraemia by polymerase chain reaction. Seroprevalence of HCV infection was 35%, while incidence was 2.4%/year; viraemia was detected in 62.5% of antiHCV+ and in only one of antiHCV-. In our opinion there is a definitive need of special precautions (or isolation of antiHCV+) in haemodialysis units to avoid community-acquired HCV infection.
为评估慢性肾衰竭患者丙型肝炎病毒感染的流行病学特征，我们在加尔加诺地区（意大利南部）的四个中心纳入了80名接受血液透析的受试者。在28个月的随访中，我们通过酶免疫测定法II检测抗丙型肝炎病毒抗体，并通过聚合酶链反应检测病毒血症。丙型肝炎病毒感染的血清流行率为35%，而发病率为每年2.4%；在抗丙型肝炎病毒抗体阳性者中有62.5%检测到病毒血症，而在抗丙型肝炎病毒抗体阴性者中仅1例检测到病毒血症。我们认为，血液透析单位绝对需要采取特殊预防措施（或隔离抗丙型肝炎病毒抗体阳性者）以避免社区获得性丙型肝炎病毒感染。
