[痉挛性截瘫患者（HAM/TSP和PEP）亲属中HTLV-I的血清阳性率]
[Seroprevalence of HTLV-I in relatives of patients with spastic paraparesis (HAM/TSP and PEP)].
作者信息
Cartier L, Vergara C, Ramírez E, Casivar T, Vásquez A
机构信息
Departamento de Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile, Santiago de Chile.
出版信息
Rev Med Chil. 1995 Jan;123(1):7-11.
The seroprevalence of HTLV-1 was studied in parents, brothers, siblings and sexual partners of 147 patients with spastic paraparesis associated to HTLV-1 (HAM/TSP) and 84 patients with HTLV-1 negative spastic paraparesis (SP). Seroprevalence was 29.1% for HAM/SP and 0% for SP relatives (p < 0.001); the last figure is similar to that of the general population. Seroprevalence in sexual partners was 65%, suggesting that sexual intercourse is the principal route of transmission. Likewise, seroprevalence in siblings of mothers with HAM/TSP or HTLV-1 positive was 17.6%, suggesting a high maternal transmission.
对147例与人类嗜T淋巴细胞病毒1型（HTLV-1）相关的痉挛性截瘫（HAM/TSP）患者以及84例HTLV-1阴性痉挛性截瘫（SP）患者的父母、兄弟、姐妹和性伴侣进行了HTLV-1血清阳性率研究。HAM/SP患者的血清阳性率为29.1%，SP患者亲属的血清阳性率为0%（p<0.001）；后者与普通人群的血清阳性率相似。性伴侣中的血清阳性率为65%，表明性交是主要传播途径。同样，患有HAM/TSP或HTLV-1阳性母亲的姐妹中的血清阳性率为17.6%，表明母婴传播率很高。
Zotero 插件