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急性髓系白血病和骨髓再生障碍的免疫功能低下儿童的曲霉病。两例报告。

Aspergillosis in immunocompromised children with acute myeloid leukemia and bone marrow aplasia. Report of two cases.

作者信息

de Aquino M Z, Brasciner A, Cristófani L M, Maluf P T, Odone Filho V, Marques H H, Heins-Vaccari E M, Lacaz C da S, de Melo N T

机构信息

Centro de Onco-Hematólogia do Instituto da Criança, Hospital das Clínicas de São Paulo, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 1994 Sep-Oct;36(5):465-9. doi: 10.1590/s0036-46651994000500012.

DOI:10.1590/s0036-46651994000500012
PMID:7569615
Abstract

Two cases of Aspergillosis in immunocompromised children are reported. Both were caused by Aspergillus flavus. Early diagnosis and treatment led to the remission of the process. One patient had acute myeloid leukemia; the fungus was isolated from the blood. The other patient with bone marrow aplasia, presented an invasive aspergillosis of the paranasal sinuses with dissemination of fungal infection; the diagnosis was obtained by histology and culture of biopsied tissue from a palatal ulceration.

摘要

报告了两例免疫功能低下儿童的曲霉病病例。两例均由黄曲霉引起。早期诊断和治疗使病情缓解。一名患者患有急性髓系白血病,真菌从血液中分离出来。另一名患有骨髓再生障碍的患者出现鼻窦侵袭性曲霉病并伴有真菌感染播散,通过对上腭溃疡活检组织进行组织学检查和培养得以确诊。

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