Muthupillai R, Lomas D J, Rossman P J, Greenleaf J F, Manduca A, Ehman R L
Mayo Clinic and Foundation, Rochester, MN 55905, USA.
Science. 1995 Sep 29;269(5232):1854-7. doi: 10.1126/science.7569924.
A nuclear magnetic resonance imaging (MRI) method is presented for quantitatively mapping the physical response of a material to harmonic mechanical excitation. The resulting images allow calculation of regional mechanical properties. Measurements of shear modulus obtained with the MRI technique in gel materials correlate with independent measurements of static shear modulus. The results indicate that displacement patterns corresponding to cyclic displacements smaller than 200 nanometers can be measured. The findings suggest the feasibility of a medical imaging technique for delineating elasticity and other mechanical properties of tissue.
本文提出了一种核磁共振成像（MRI）方法，用于定量绘制材料对谐波机械激励的物理响应。所得图像可用于计算局部力学性能。利用MRI技术在凝胶材料中获得的剪切模量测量值与静态剪切模量的独立测量值相关。结果表明，可以测量对应于小于200纳米循环位移的位移模式。这些发现表明了一种医学成像技术用于描绘组织弹性和其他力学性能的可行性。
