Fock K M, Tay H H, Phua K B, Guan R, Chia S C, Chong R, Chee A E, Chew C N
National Foundation for Digestive Disease (NFDD) 1991-1992, Singapore.
Singapore Med J. 1995 Feb;36(1):26-7.
At the 4th National Foundation for Digestive Disease (NFDD) Day in 1991 where public lectures on prevention of hepatitis and early detection of hepatocellular carcinoma were given, screening of sera obtained from 364 registrants for antibodies to Hepatitis A (IgG) was undertaken. The overall sero-prevalence rate was 50%, with 55% for males and 46% for females with antibodies for HAV. None of the subjects below 20 years old had antibodies to HAV. This rose to 16% for those 21-30 years old and 92% for those above 61 years. This study shows that in Singapore, prevalence of anti-HAV antibodies rise with age and is approaching the low endemicity pattern that is seen in developed countries.
在1991年第四届全国消化系统疾病基金会(NFDD)日举办了关于肝炎预防和肝细胞癌早期检测的公开讲座,期间对364名登记参与者的血清进行了甲型肝炎抗体(IgG)筛查。总体血清流行率为50%,男性有甲型肝炎抗体的比例为55%,女性为46%。20岁以下的受试者均无甲型肝炎抗体。21至30岁的人群中这一比例升至16%,61岁以上人群则为92%。这项研究表明,在新加坡,抗甲型肝炎抗体的流行率随年龄增长而上升,正接近发达国家所见的低流行模式。