Kempen G I, Brilman E I, Ormel J
Noordelijk Centrum voor Gezondheidsvraagstukken, Rijksuniversiteit Groningen.
Tijdschr Gerontol Geriatr. 1995 Aug;26(4):163-72.
The results of a study on the comparison of the original 20-item Mini-Mental State Examination with a shortened 12-item version as a brief screening test for cognitive impairments in a community based older sample are presented. The scores on the MMSE decrease with higher ages and lower levels of education. The results show that a threshold value of 24 on the MMSE-20 (Cohen's kappa .70), which supports previous Norwegian findings. In case of the identification of older people with severe cognitive impairments -threshold value 17 or 18 on the MMSE-20-, we found a corresponding threshold on the MMSE-12 of 7 (Cohen's kappa .87 and .91, respectively). Although the Norwegian researchers made no direct comparison between the MMSE-20 and MMSE-12 for these lower thresholds, a threshold 7 on the MMSE-12 resulted in a lower level of misclassifications of cognitively impaired patients by a psychogeriatrician compared to a threshold of 18 on the MMSE-20. It may be concluded that the MMSE-12, which is simpler to use and takes less time, has the same diagnostic properties as a screening tool for mild and severe cognitive impairments.
本文展示了一项研究结果，该研究旨在比较最初的20项简易精神状态检查表（Mini-Mental State Examination，MMSE）与缩短为12项的版本，以作为对社区老年样本认知障碍的简短筛查测试。MMSE得分会随着年龄增长和教育水平降低而下降。结果表明，MMSE-20的阈值为24（科恩kappa系数为0.70），这与挪威之前的研究结果相符。在识别严重认知障碍的老年人时（MMSE-20的阈值为17或18），我们发现MMSE-12的相应阈值为7（科恩kappa系数分别为0.87和0.91）。尽管挪威研究人员没有对MMSE-20和MMSE-12在这些较低阈值上进行直接比较，但与MMSE-20的阈值18相比，MMSE-12的阈值7导致老年精神科医生对认知障碍患者的误分类水平更低。可以得出结论，使用更简便且耗时更少的MMSE-12作为轻度和重度认知障碍的筛查工具，具有相同的诊断特性。
