Kreze A, Kuviková A, Laca L, Kompis S, Dobáková M, Babusík P, Matecek L, Pekárová E
Interná klinika A Nemocnice F. D. Roosevelta, Banská Bystrica.
Vnitr Lek. 1995 Jul;41(7):470-2.
The authors describe a patient with hyperthyroidism who developed after three weeks' treatment with carbimazole agranulocytosis and the condition was complicated by septic shock. The authors used for treatment in addition to antibiotics and corticoids, for the first time in their practice, human recombinant granulocyte macrophage colonies stimulating factor (rHuGM-CSF) which produced a very favourable effect. In the meantime the patient was prepared for goitrectomy, operated and discharged in a satisfactory condition to have ambulatory treatment.
作者描述了一名甲状腺功能亢进患者，在用卡比马唑治疗三周后发生了粒细胞缺乏症，且病情因感染性休克而复杂化。作者在其临床实践中首次除使用抗生素和皮质类固醇外，还使用了重组人粒细胞巨噬细胞集落刺激因子（rHuGM-CSF）进行治疗，该治疗产生了非常良好的效果。与此同时，为患者准备了甲状腺切除术，手术顺利，患者出院时情况良好，接受门诊治疗。
