台北市儿童幽门螺杆菌感染的血清流行病学研究。

Seroepidemiologic study of Helicobacter pylori infection in children in Taipei city.

作者信息

Tsai C J, Chang M H

机构信息

Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.

出版信息

Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1995 Jul-Aug;36(4):254-6.

PMID:7572166

Abstract

To study the epidemiology of Helicobacter pylori (H. pylori) infection in children, the presence of the IgG antibody against H. pylori was evaluated by enzyme-linked immunosorbent assay (ELISA) method in unselected children in Taipei city. Serum samples were collected there from 428 apparently healthy children under 12 years of age. The overall prevalence of H. pylori infection was 8.4%. A low prevalence was found in the groups 1-3 years old (0.9%) and 3-6 years old (3.7%). The prevalence rate increased significantly after 6 years of age, and reached 19.4% at 9-12 years of age. In conclusion, H. pylori infection was independent of gender, but increased with age.

摘要

为研究儿童幽门螺杆菌（H. pylori）感染的流行病学，采用酶联免疫吸附测定（ELISA）法对台北市未筛选儿童中抗H. pylori IgG抗体的存在情况进行了评估。从428名12岁以下看似健康的儿童中采集了血清样本。H. pylori感染的总体患病率为8.4%。在1 - 3岁组（0.9%）和3 - 6岁组（3.7%）中发现患病率较低。6岁以后患病率显著上升，在9 - 12岁时达到19.4%。总之，H. pylori感染与性别无关，但随年龄增长而增加。