不同嗜酸性粒细胞增多症中白细胞介素-5、粒细胞-巨噬细胞集落刺激因子和白细胞介素-3的血清浓度以及淋巴细胞的产生情况。
Serum concentrations of IL-5, GM-CSF, and IL-3 and the production by lymphocytes in various eosinophilia.
作者信息
Koike T, Enokihara H, Arimura H, Ninomiya H, Yamashiro K, Tsuruoka N, Tsujimoto M, Aoyagi M, Watanabe K, Nakamura Y
机构信息
Third Department of Internal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.
出版信息
Am J Hematol. 1995 Oct;50(2):98-102. doi: 10.1002/ajh.2830500205.
The concentrations of interleukin-5 (IL-5), granulocyte-macrophage colony-stimulating factor GM-CSF, and interleukin-3 (IL-3) in serum and in IL-2-stimulated lymphocyte culture medium (L-IL2-CM) prepared from patients with reactive eosinophilia were measured by enzyme-linked immunosorbent assay (ELISA). Serum IL-5 levels were increased in 16 out of 42 cases. GM-CSF and IL-3 were below the detectable levels in all sera examined. The concentrations of IL-5 and GM-CSF in L-IL2-CM were increased in 10 out of 29 patients. IL-3 was below the detectable levels in all L-IL2-CM.
采用酶联免疫吸附测定法（ELISA）检测反应性嗜酸性粒细胞增多症患者血清及白细胞介素-2（IL-2）刺激的淋巴细胞培养基（L-IL2-CM）中白细胞介素-5（IL-5）、粒细胞-巨噬细胞集落刺激因子（GM-CSF）和白细胞介素-3（IL-3）的浓度。42例患者中有16例血清IL-5水平升高。在所有检测的血清中，GM-CSF和IL-3低于可检测水平。29例患者中有10例L-IL2-CM中IL-5和GM-CSF浓度升高。在所有L-IL2-CM中，IL-3低于可检测水平。
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