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长期给予玉米赤霉烯酮对雄性大鼠精子发生及血清促黄体生成素、促卵泡生成素和催乳素值的影响。

Effects of long-term zearalenone administration on spermatogenesis and serum luteinizing hormone, follicle-stimulating hormone, and prolactin values in male rats.

作者信息

Milano G D, Becú-Villalobos D, Tapia M O

机构信息

Departamento de Fisiopatología, Facultad de Ciencias Veterinarias, Universidad del Centro de la Provincia de Buenos Aires, Argentina.

出版信息

Am J Vet Res. 1995 Jul;56(7):954-8.

PMID:7574167
Abstract

Body and testis weights, serum luteinizing hormone, follicle-stimulating hormone, and prolactin values and volume fractions of Sertoli cells, spermatogonia, early and late primary spermatocytes, and round and long spermatids were evaluated in 70-day-old male rates treated orally with 20 mg of zearalenone/kg of body weight daily for 5 weeks. Significant (P < 0.05) increase in serum prolactin concentration was consistently observed during the 5 weeks of treatment with zearalenone. Significant changes were not observed in any of the other variables evaluated.

摘要

对70日龄雄性大鼠进行评估,这些大鼠每天经口给予20毫克玉米赤霉烯酮/千克体重,持续5周,评估其体重、睾丸重量、血清促黄体生成素、促卵泡生成素、催乳素值以及支持细胞、精原细胞、早期和晚期初级精母细胞、圆形和长形精子细胞的体积分数。在玉米赤霉烯酮治疗的5周期间,始终观察到血清催乳素浓度显著(P<0.05)升高。在评估的任何其他变量中均未观察到显著变化。

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Involvement of the Fas and Fas ligand in testicular germ cell apoptosis by zearalenone in rat.玉米赤霉烯酮诱导大鼠睾丸生殖细胞凋亡中Fas及Fas配体的作用
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