Gwaltney J M, Jones J G, Kennedy D W
Ann Otol Rhinol Laryngol Suppl. 1995 Oct;167:22-30.
The primary goal of sinusitis management is resolution of infection, leading to patency of the ostiomeatal complex. Antibiotics and decongestants are the cornerstones of therapy for acute sinusitis. Diagnosis of acute sinusitis is based on the history and physical findings. Sinusitis is considered to be acute or recurrent acute if infection resolves without residual mucosal damage. Choices for first-line antibiotic therapy include adequate dosages of trimethoprim-sulfamethoxazole, loracarbef, and amoxicillin-clavulanate. Decongestants and mucoevacuants may reduce tissue edema, facilitate drainage, and maintain ostial patency. Topical corticosteroids are useful additional therapy in allergic rhinosinusitis and as an aid in the long-term management of chronic sinusitis. Parenteral corticosteroids have no role in first-line management of acute or recurrent acute sinusitis.
鼻窦炎治疗的主要目标是消除感染,使窦口鼻道复合体通畅。抗生素和解充血剂是急性鼻窦炎治疗的基石。急性鼻窦炎的诊断基于病史和体格检查结果。如果感染消退且无残留黏膜损伤,则鼻窦炎被认为是急性或复发性急性。一线抗生素治疗的选择包括足量的甲氧苄啶 - 磺胺甲恶唑、氯碳头孢和阿莫西林 - 克拉维酸。解充血剂和黏液促排剂可减轻组织水肿、促进引流并保持窦口通畅。局部用皮质类固醇在变应性鼻鼻窦炎中是有用的辅助治疗,也有助于慢性鼻窦炎的长期管理。胃肠外皮质类固醇在急性或复发性急性鼻窦炎的一线治疗中不起作用。