Natsume J, Watanabe K, Kuno K, Hayakawa F, Hashizume Y
Department of Pediatrics, Nagoya University School of Medicine, Anjo Kosei Hospital, Japan.
Pediatr Neurol. 1995 Jul;13(1):61-4. doi: 10.1016/0887-8994(95)00054-j.
An infant who demonstrated clinical features compatible with total asphyxia is reported. Immediately after birth, the patient manifested severe hypotonia and total absence of cranial nerve functions. Magnetic resonance imaging revealed abnormal intensity of the thalamus and putamen, and atrophy of the brainstem. Late components of brainstem auditory evoked potential were absent, but electroencephalography was normal. Postmortem autopsy revealed destructive lesions of the brainstem tegmentum, thalamus, basal ganglia, and spinal cord, but preserved cerebral cortex; findings consistent with those of total asphyxia as reported by Myers, and attributable to prenatal insult.
报告了一名表现出与完全窒息相符的临床特征的婴儿。出生后即刻，该患者表现出严重的肌张力减退和完全缺乏颅神经功能。磁共振成像显示丘脑和壳核信号异常，以及脑干萎缩。脑干听觉诱发电位的晚期成分缺失，但脑电图正常。尸检显示脑干被盖、丘脑、基底神经节和脊髓有破坏性病变，但大脑皮层保存；这些发现与迈尔斯报道的完全窒息的发现一致，且归因于产前损伤。
