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[慢性尿毒症患者每周进行腹膜透析的长期生存情况]

[Prolonged survival with weekly peritoneal dialysis in chronic uremic patients].

作者信息

Treviño Becerra A, Jauregui Ontiveros B

出版信息

Prensa Med Mex. 1978 Nov-Dec;43(11-12):302-7.

PMID:757607
Abstract

We show our experience in 12 patients treated during a year with weekly intermittent dialysis whit a rigid catheter for 36 hours a week. Patients were on a diet of 50 g. of proteins a day, normocaloric without sodium or fluid restriction. They received supplementation whith iron, calcium, vitamins B, C and folic acid, anabolic hormonal and, in some cases, furosemide hypotensives and antibiotics. Patients received the procedure for a mean of 8 months. The results show the following mean values: blood pressure: 143 +/- 12/99 +/- 3 mm. Hg., plasma urea 208 +/- 62 ng./dl.; creatinine 21 +/- 2 mg./dl., hematocrit 25 mm. and 8.0 g. hemoglobin. There was light increase of glucose, K, P, Mg, alkaline phosphatase. Na, CO2, proteins cholesterol, albumin and Ca keep in normal values. Nine patients passed to hemodialysis after a mean period of nine months and three of them received a kidney transplant. Three are still in peritoneal dialysis, one of them for 18 months. We compared our results with a similar group of patients who were treated with non-regular peritoneal dialysis. Our group had less cardiovascular complaints, or infections and keep more adequate body weight, and also got more survival in better conditions with less days in hospital, they received less blood transfusion. We concluded that weekly peritoneal dialysis is an alternative method of treatment in uremic patients for longer period of time even though frequently paracentesis.

摘要

我们展示了在一年中对12例患者进行每周间歇性透析的经验,使用硬质导管,每周透析36小时。患者每天摄入50克蛋白质的饮食,热量正常,无钠或液体限制。他们接受铁、钙、维生素B、C和叶酸补充,使用合成代谢激素,在某些情况下还使用速尿降压药和抗生素。患者接受该治疗的平均时间为8个月。结果显示以下平均值:血压:143±12/99±3毫米汞柱;血浆尿素208±62纳克/分升;肌酐21±2毫克/分升;血细胞比容25%,血红蛋白8.0克。血糖、钾、磷、镁、碱性磷酸酶略有升高。钠、二氧化碳、蛋白质、胆固醇、白蛋白和钙保持在正常水平。9例患者在平均9个月后转为血液透析,其中3例接受了肾移植。3例仍在进行腹膜透析,其中1例已进行18个月。我们将我们的结果与一组接受非定期腹膜透析的类似患者进行了比较。我们的患者心血管问题、感染较少,体重维持得更合适,并且在更好的条件下有更高的生存率,住院天数更少,输血次数也更少。我们得出结论,每周腹膜透析是尿毒症患者较长时间的一种替代治疗方法,尽管需要频繁进行腹腔穿刺。

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