Klein E E, Wasserman T, Ermer B
Mallinckrodt Institute of Radiology, Radiation Oncology Center, Jewish Hospital of Washington University Medical School, St. Louis, MO 63110, USA.
Med Dosim. 1995 Fall;20(3):171-6. doi: 10.1016/0958-3947(95)00022-o.
There are occasions when patients can benefit significantly from being treated upright. This technique is beneficial in the treatment of Hodgkin's disease when the mediastinum is involved. The main benefit is the lung volume spared resulting from narrowing of a bulky mediastinum. We purchased a commercial treatment chair to facilitate upright treatment. Clinical implementation required rigorous testing, documentation of procedures, and acknowledgment of and corresponding solutions to limitations. The purchased chair is designed to couple with the spine bar of the treatment couch, allowing patient positioning via pendant functions. The chair has no obstruction as immobilization is afforded by arm, shoulder, and knee supports, which allows isocentric treatments. An additional hydraulic mount is used for simulation. We have treated five patients thus far, including Hodgkin's disease patients with and without mediastinal involvement, and one lung cancer patient with a large lower lobe lesion. All patients have benefited by having a greater volume of lung spared (as much as 60% additional blocking) when upright simulation films are compared with supine and prone films. Immobilization has been adequate as confirmed by daily light field projections and portal films. We are routinely evaluating Hodgkin's disease patients for upright treatment. Patients treated in the chair have benefited in terms of lung volume spared without loss of immobilization. A patient with a large lower lobe lung lesion has also benefited as the tumor "dropped," thus affording lung sparing via blocking.
有些情况下,患者采用直立位治疗可显著获益。该技术在治疗累及纵隔的霍奇金病时有益。主要益处是因肿大纵隔变窄而保留的肺容积。我们购买了一台商用治疗椅以方便直立位治疗。临床实施需要严格测试、记录操作流程,并认识到局限性并给出相应解决方案。所购治疗椅设计为与治疗床的脊柱杆相连,可通过手持控制装置进行患者定位。该治疗椅无障碍物,通过手臂、肩部和膝盖支撑实现固定,从而可进行等中心治疗。另外使用一个液压支架进行模拟。到目前为止,我们已治疗了5例患者,包括有和没有纵隔受累的霍奇金病患者,以及1例下叶有大病灶的肺癌患者。与仰卧位和俯卧位片相比,所有患者在直立位模拟片时都因保留了更大的肺容积(额外遮挡多达60%)而获益。通过每日的灯光野投照和射野片证实固定效果良好。我们正在常规评估霍奇金病患者进行直立位治疗的情况。在治疗椅上接受治疗的患者在保留肺容积且不影响固定的情况下获益。1例下叶有大病灶的肺癌患者也因肿瘤“下垂”而获益,从而通过遮挡实现了肺的保留。