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直立位斗篷野照射:一种减少纵隔巨大霍奇金病患者肺部受照射体积的技术。

Mantle irradiation in the upright position: a technique to reduce the volume of lung irradiated in patients with bulky mediastinal Hodgkin's disease.

作者信息

Marcus K C, Svensson G, Rhodes L P, Mauch P M

机构信息

Department of Radiation Therapy, Harvard Medical School, Boston, MA.

出版信息

Int J Radiat Oncol Biol Phys. 1992;23(2):443-7. doi: 10.1016/0360-3016(92)90766-b.

Abstract

Many patients with mediastinal Hodgkin's disease radiographically show a wider horizontal width of disease in the supine or prone as compared to the upright position. Yet for most patients mantle treatment in the supine/prone position is still preferable. This position allows good patient immobilization and precise matching between the mantle and paraaortic-splenic pedicle fields that would not be possible in the sitting or upright position. Adequate blocking of the lungs and heart remains possible in the supine position since most patients do not have extensive subcarinal Hodgkin's disease. Even when more extensive disease is present, contoured blocks to protect the heart and lungs can be adjusted to protect a greater portion of normal tissues if the mediastinal nodes respond to treatment. But if sizeable mediastinal disease persists, it may be impossible to protect sufficient heart and lung. Under these circumstances, repositioning the patient upright can shift the configuration of the mass, allowing larger lung blocks to be added. We report the use of a chair to facilitate treatment with mantle irradiation in the upright position for patients whose mediastinal disease when supine is too large to allow adequate blocking of heart and lung. Blocks are made from the initial port films and daily treatment films are taken to confirm an accurate set-up. To avoid excessive dose to the spinal cord, patients who are to receive para-aortic irradiation receive a maximum of 15-20 Gy in the upright position and the remainder of the mantle is given in the supine-prone position. The use of the upright technique allows for the use of radiation in patients who would otherwise be unable to receive adequate doses due to potential lung and cardiac toxicity.

摘要

许多纵隔霍奇金病患者的影像学检查显示,与直立位相比,仰卧位或俯卧位时疾病的水平宽度更宽。然而,对于大多数患者来说,仰卧/俯卧位进行斗篷野治疗仍然是更可取的。这个体位能使患者很好地固定,并且斗篷野与腹主动脉-脾蒂野之间能精确匹配,而这在坐位或直立位是无法做到的。由于大多数患者没有广泛的隆突下霍奇金病,所以在仰卧位仍可对肺和心脏进行充分的遮挡。即使存在更广泛的病变,如果纵隔淋巴结对治疗有反应,用于保护心脏和肺的成形挡块可以进行调整,以保护更大范围的正常组织。但如果纵隔病变持续较大,可能无法充分保护心脏和肺。在这种情况下,将患者重新置于直立位可改变肿块的形态,从而能增加更大的肺部挡块。我们报告了使用一种椅子来方便对仰卧位时纵隔病变过大而无法充分遮挡心脏和肺的患者进行直立位斗篷野照射治疗。挡块根据初始射野片制作,每天拍摄治疗片以确认摆位准确。为避免脊髓接受过量照射,接受腹主动脉照射的患者在直立位最多接受15 - 20 Gy照射,斗篷野的其余部分在仰卧-俯卧位给予。直立技术的应用使得那些因潜在的肺部和心脏毒性而原本无法接受足够剂量照射的患者能够接受放疗。

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