各种息肉病综合征的表型与癌症风险

Phenotype and cancer risk of various polyposis syndromes.

作者信息

Giardiello F M, Offerhaus J G

机构信息

Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.

出版信息

Eur J Cancer. 1995 Jul-Aug;31A(7-8):1085-7. doi: 10.1016/0959-8049(95)00139-a.

DOI:10.1016/0959-8049(95)00139-a

PMID:7576997

Abstract

The gastrointestinal polyposis syndromes are disorders with multiple intestinal polyps. Three of these disorders, familial adenomatous polyposis, Peutz-Jeghers syndrome and juvenile polyposis are associated with increased risk of colorectal as well as extracolonic cancers. A description of the phenotype and associated cancer risk is provided for each.

摘要

胃肠道息肉综合征是一种伴有多个肠道息肉的病症。其中三种病症，即家族性腺瘤性息肉病、黑斑息肉综合征和幼年性息肉病，与结直肠癌以及结肠外癌症的风险增加有关。文中对每种病症的表型及相关癌症风险进行了描述。