法国三个地区非小细胞肺癌的治疗差异和生存率
Differences in treatment and survival rates of non-small-cell lung cancer in three regions of France.
作者信息
Grosclaude P, Galat J P, Macé-Lesech J, Roumagnac-Machelard M, Mercier M, Robillard J
机构信息
Registre des cancers du Tarn, chemin des trois Tarn, Albi, France.
出版信息
Br J Cancer. 1995 Nov;72(5):1278-82. doi: 10.1038/bjc.1995.500.
Treatment and survival rates of patients with non-small-cell lung cancer (NSCLC) were compared between three French Cancer Registries (Calvados, Doubs, Tarn). The methodological issues in such comparisons are discussed. The treatments for NSCLC differed between the regions: radiotherapy tended to be preferred in Calvados (73% vs 21.3% surgery), whereas surgery was more frequently employed in Doubs and Tarn (27.7% and 37% respectively). The percentage of cases receiving no therapeutic treatment ranged from 7.8% (Calvados) to 26% (Tarn). Despite the differences in treatment, the overall survival rates were similar in the three regions. Adjustment for treatment in such a descriptive study may be misleading since different therapeutic strategies in different regions may lead to selection of patients of systematically better or poorer prognosis in the various treatment groups.
在法国的三个癌症登记处（卡尔瓦多斯、杜省、塔恩省）之间比较了非小细胞肺癌（NSCLC）患者的治疗情况和生存率。讨论了此类比较中的方法学问题。NSCLC的治疗方法在不同地区有所不同：卡尔瓦多斯地区倾向于首选放疗（73%，而手术为21.3%），而杜省和塔恩省更常采用手术（分别为27.7%和37%）。未接受任何治疗的病例百分比从7.8%（卡尔瓦多斯）到26%（塔恩省）不等。尽管治疗方法存在差异，但三个地区的总体生存率相似。在这样的描述性研究中对治疗进行调整可能会产生误导，因为不同地区不同的治疗策略可能导致在各个治疗组中系统性地选择预后较好或较差的患者。
Zotero 插件