Warrer K, Buser D, Lang N P, Karring T
Royal Dental College, Aarhus, Denmark.
Clin Oral Implants Res. 1995 Sep;6(3):131-8. doi: 10.1034/j.1600-0501.1995.060301.x.
In 5 monkeys a total of 30 transmucosal endosseous dental implants were inserted in edentulous areas of the mandible with presence or absence of keratinized mucosa. After a healing period of 3 months with optimal plaque control, all implants were exposed to plaque accumulation for periods up to 9 months. To secure abundant plaque accumulation on half the number of the implants, cotton wool ligatures were placed around the implants at the entrance to the peri-implant sulcus. Attachment loss was measured clinically and histometrically, and tissue recession was measured clinically. Ligated implants without keratinized mucosa demonstrated significantly more recession and slightly more attachment loss than the other implants. The results of this study suggest that the absence of keratinized mucosa around dental endosseous implants increases the susceptibility of the peri-implant region to plaque-induced tissue destruction.
在5只猴子的下颌无牙区植入了总共30颗经黏膜骨内牙种植体，这些区域存在或不存在角化黏膜。在进行了3个月的愈合期并实现最佳菌斑控制后，所有种植体暴露于菌斑积聚环境中长达9个月。为确保一半数量的种植体上有大量菌斑积聚，在种植体周围的种植体沟入口处放置了棉线结扎。临床和组织测量法测量附着丧失，临床测量组织退缩。没有角化黏膜的结扎种植体比其他种植体表现出明显更多的退缩和稍多的附着丧失。本研究结果表明，牙骨内种植体周围缺乏角化黏膜会增加种植体周围区域对菌斑诱导的组织破坏的易感性。
