Pascual J, Liaño F, Ortuño J
J Am Soc Nephrol. 1995 Aug;6(2):144-53. doi: 10.1681/ASN.V62144.
Structural and functional changes observed in the aging kidney predispose the elderly patient to acute renal failure. Up to 36% of the patients with acute renal failure from this institution were over 70 yr, and the literature is full of similar experiences. The elderly patient with abrupt cessation of adequate renal function requires a special work-up in diagnosis and treatment. Prerenal and obstructive causes are of particular interest. Although the question of whether or not age has an independent prognostic importance during an episode of acute renal failure remains debated; when these and other authors compared the outcome of young and old populations with these disorders, a similar evolution was always observed. Age should not be used as a discriminant factor in therapeutic decisions concerning acute renal failure.
衰老肾脏中观察到的结构和功能变化使老年患者易患急性肾衰竭。该机构高达36%的急性肾衰竭患者年龄超过70岁，并且文献中充斥着类似的情况。肾功能突然充分丧失的老年患者在诊断和治疗方面需要进行特殊检查。肾前性和梗阻性病因尤其值得关注。尽管在急性肾衰竭发作期间年龄是否具有独立的预后重要性这一问题仍存在争议；但当这些作者以及其他作者比较患有这些疾病的年轻和老年人群的预后时，总是观察到相似的病情发展。在急性肾衰竭的治疗决策中，年龄不应作为一个判别因素。
