Messer J, Tongio M M, Willard D, Mayer S, Daltroff G
Arch Fr Pediatr. 1978 Oct;35(8):875-80.
A severe neutropenia in a 2 day old newborn drew attention to anti-HLA and NA 2 antigranulocytic antibodies in the maternal serum. Close supervision from birth of a younger sibling demonstrated a neutropenia on the 5th day of life. Serological investigation showed the anti-NA 2 antibody to be responsible in both cases. A good result with total blood replacement of leucocyte-free blood in the second case would advocate this treatment in cases of severe immunological neutropenia.
一名2日龄新生儿的严重中性粒细胞减少症引起了对母体血清中抗HLA和抗NA 2抗粒细胞抗体的关注。对一名较年幼同胞自出生起进行密切监测，发现其在出生后第5天出现中性粒细胞减少症。血清学调查显示，两例病例均由抗NA 2抗体所致。第二例病例中采用无白细胞全血置换取得了良好效果，这表明对于严重免疫性中性粒细胞减少症病例可采用这种治疗方法。
