Cope C
Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
J Vasc Interv Radiol. 1995 Jul-Aug;6(4):546-52. doi: 10.1016/s1051-0443(95)71132-0.
To assess the efficacy of rare-earth magnets for creating a cholecystogastrostomy (CG) or cholecystojejunostomy (CJ) in nine swine.
Neodymium-iron-boron magnets or rare-earth cobalt magnets of various configuration and strength were coupled in pairs to form four CGs and five CJs. Magnets were implanted surgically in the gallbladder and jejunum, and perorally in the stomach. Gross and histologic examinations of anastomoses were performed 8-16 days later.
All anastomoses showed good adhesion with no leakage and minimal inflammation. Anastomoses were fully patent in four CJs and one CG (mean, 12 days), partially patent in one CJ and one CG (mean, 15 days), and not patent in two CGs. Best results were noted with jacketed disc magnets with cutting rims and a 400-600-g pull. The rare-earth magnets were significantly weakened by gas sterilization in the first four CG experiments. Two of four magnets used in CJ were retained despite a fully patent anastomosis.
Leak-free patent or partially patent cholecystenteric anastomoses were created by magnet compression in 9-16 days. This technique may have clinical interventional applications.
评估稀土磁体在9头猪身上创建胆囊胃吻合术（CG）或胆囊空肠吻合术（CJ）的效果。
将各种形状和强度的钕铁硼磁体或稀土钴磁体成对耦合，形成4个CG和5个CJ。磁体通过手术植入胆囊和空肠，并经口植入胃内。8 - 16天后对吻合口进行大体和组织学检查。
所有吻合口均显示良好粘连，无渗漏且炎症轻微。4个CJ和1个CG的吻合口完全通畅（平均12天），1个CJ和1个CG的吻合口部分通畅（平均15天），2个CG的吻合口不通畅。带切割边缘且拉力为400 - 600克的夹套圆盘磁体效果最佳。在前4个CG实验中，气体灭菌使稀土磁体显著减弱。尽管吻合口完全通畅，但用于CJ的4个磁体中有2个被保留。
通过磁体压迫在9 - 16天内创建了无渗漏的通畅或部分通畅的胆囊肠吻合口。该技术可能具有临床介入应用价值。
