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通过经口、经皮或手术方式引入磁体创建压迫性胃肠吻合术:猪的可行性研究

Creation of compression gastroenterostomy by means of the oral, percutaneous, or surgical introduction of magnets: feasibility study in swine.

作者信息

Cope C

机构信息

Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.

出版信息

J Vasc Interv Radiol. 1995 Jul-Aug;6(4):539-45. doi: 10.1016/s1051-0443(95)71131-9.

Abstract

PURPOSE

The use of magnets placed surgically, percutaneously, and orally to create compression gastroenteric anastomoses was evaluated in 11 swine.

MATERIALS AND METHODS

Disc-shaped, jacketed rare-earth magnets with cutting edges varying in diameter from 0.250 inch (6.4 mm) to 0.500 inch (12.7 mm) were used in seven swine, and rectangular types were used in three swine. Magnets were implanted surgically in five and introduced by means of standard interventional techniques through a gastrostomy in two and perorally in four animals. Anastomoses (n = 8) were studied grossly and histologically for acute changes at 5-13 days and for 30-day patency in one.

RESULTS

Of the nine surviving pigs, there were seven completely patent anastomoses and one partially patent anastomosis at 7-13 days. At 5 days the anastomosis was not patent in the remaining animal. One anastomosis became occluded at 30 days. There was no anastomotic leakage, infection, or bleeding.

CONCLUSIONS

Leak-free gastrojejunostomies can be created by inserting magnets perorally, percutaneously, or surgically.

摘要

目的

在11头猪身上评估通过手术、经皮和口服放置磁体来创建压迫性胃肠吻合术的应用情况。

材料与方法

七头猪使用了直径从0.250英寸(6.4毫米)到0.500英寸(12.7毫米)不等的带刃圆盘形包裹稀土磁体,三头猪使用了矩形磁体。五头猪通过手术植入磁体,两头猪通过标准介入技术经胃造口术引入磁体,四头猪经口引入磁体。对8个吻合口进行大体和组织学研究,观察5至13天的急性变化以及1个吻合口30天的通畅情况。

结果

在9头存活的猪中,7至13天时,有7个吻合口完全通畅,1个部分通畅。在第5天时,其余那头猪的吻合口不通畅。1个吻合口在30天时闭塞。未发生吻合口漏、感染或出血。

结论

经口、经皮或手术插入磁体可创建无漏的胃空肠吻合术。

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