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[慢性特发性血小板减少性紫癜免疫变化与中医辨证分型及预后关系的初步分析]

[Preliminary analysis of relationship between immunological changes and syndrome differentiation-typing in traditional Chinese medicine and prognosis with chronic idiopathic thrombocytopenic purpura].

作者信息

Yang Y F, Zhou A X, Ma R

机构信息

Dept. of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Jul;15(7):401-4.

PMID:7580059
Abstract

In order to study the relationship between the basement immunological changes, TCM Syndrome Differentiation and prognosis, alkaline phosphates antialkaline phosphatase (APAAP) and ELISA assay were used to determine the T lymphocyte subsets, the platelet associated antibody (PAIgG, PAIgA, PAIgM) and plasma antiplatelet-autoantibodies (GP II b, GP III a, GP I b) in 55 chronic idiopathic thrombocytopenic purpura (ITP) and 53 healthy subjects as control. The results indicated that the immunological changes was closely related to the prognosis, while the TCM Syndrome Differentiation was also related to it, which denoted that it is significant to investigate both factors in guiding treatment and assessing the prognosis.

摘要

为研究免疫功能变化、中医辨证与预后的关系,采用碱性磷酸酶抗碱性磷酸酶桥联酶标法(APAAP)和酶联免疫吸附试验(ELISA)检测55例慢性特发性血小板减少性紫癜(ITP)患者及53例健康对照者的T淋巴细胞亚群、血小板相关抗体(PAIgG、PAIgA、PAIgM)和血浆抗血小板自身抗体(GPⅡb、GPⅢa、GPⅠb)。结果表明,免疫功能变化与预后密切相关,中医辨证也与之相关,提示两者对指导治疗和判断预后均有重要意义。

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