由于不同的精神刺激，大脑氧合和血流动力学存在区域依赖性的不对称或对称变化。

Region-dependent asymmetrical or symmetrical variations in the oxygenation and hemodynamics of the brain due to different mental stimuli.

作者信息

Okada F, Tokumitsu Y, Takahashi N, Hoshi Y, Tamura M

机构信息

Health Administration Center, Hokkaido University, Sapporo, Japan.

出版信息

Brain Res Cogn Brain Res. 1995 Jul;2(3):215-9. doi: 10.1016/0926-6410(95)90010-1.

DOI:10.1016/0926-6410(95)90010-1

PMID:7580403

Abstract

The present paper demonstrates region-dependent variations in the oxygenation and hemodynamics of the brain hemispheres due to three different types of mental stimulation. The variations were observed with a four-channel optical imaging system using tissue-transparent near-infrared light and described changes from baseline of both the hemoglobin oxygenation state and blood volume during three kinds of psychological or mental tasks. During the mirror drawing task, a lateralized hemisphere response (the dominant hemisphere response pattern) was observed in 57% of 14 right handed volunteers in the frontal region (Brodmann's area 10), while in the temporal region (area 38), 80% showed the bilateral response pattern. A large majority of the subjects showed the bilateral response pattern in the frontal and temporal regions while calculating. A smaller majority showed this while looking at anatomical charts, though 30% did not show any response at all in the temporal region. This showed that there were region-dependent asymmetrical or symmetrical variations of the oxygen delivery-oxygen utilization relationship due to different types of mental stimuli.

摘要

本文证明了由于三种不同类型的精神刺激，大脑半球的氧合和血流动力学存在区域依赖性变化。使用组织透明近红外光的四通道光学成像系统观察到了这些变化，并描述了在三种心理或精神任务期间血红蛋白氧合状态和血容量相对于基线的变化。在镜像绘制任务中，14名右利手志愿者中有57%在额叶区域（布罗德曼区10）观察到半球侧化反应（优势半球反应模式），而在颞叶区域（38区），80%表现出双侧反应模式。在计算时，绝大多数受试者在额叶和颞叶区域表现出双侧反应模式。在查看解剖图时，较小比例的多数人表现出这种模式，尽管30%的人在颞叶区域根本没有任何反应。这表明，由于不同类型的精神刺激，氧输送-氧利用关系存在区域依赖性的不对称或对称变化。