人类在进行脑力任务时神经元活动、氧化代谢和血液供应的不同步行为。
Non-synchronous behavior of neuronal activity, oxidative metabolism and blood supply during mental tasks in man.
作者信息
Hoshi Y, Onoe H, Watanabe Y, Andersson J, Bergström M, Lilja A, Långström B, Tamura M
机构信息
Institute for Electronic Science, Hokkaido University, Sapporo, Japan.
出版信息
Neurosci Lett. 1994 May 19;172(1-2):129-33. doi: 10.1016/0304-3940(94)90679-3.
In near-infrared spectroscopic studies during mental tasks such as problem solving and mental arithmetic, we found that 9 of 33 healthy volunteers showed decreases in both the regional cerebral blood flow (r-CBF) and oxygen consumption rate (CMRO2) in the frontal region of the dominant hemisphere. To confirm these unexpected observations, we performed simultaneous measurements by positron emission tomography (PET) and near-infrared spectroscopy (NIRS) in two such subjects. PET images also showed that CBF decreased within the presumptive area illuminated by near-infrared light during mental task. However, CBF decreased in almost all regions while the subject gave a correct answer. Thus, the questions arose: Are mental tasks always associated with increases in r-CBF and/or CMRO2?
在诸如解决问题和心算等思维任务期间进行的近红外光谱研究中，我们发现，33名健康志愿者中有9人在优势半球额叶区域的局部脑血流量（r-CBF）和氧消耗率（CMRO2）均出现下降。为了证实这些意外的观察结果，我们对两名此类受试者进行了正电子发射断层扫描（PET）和近红外光谱（NIRS）同步测量。PET图像还显示，在思维任务期间，近红外光照射的假定区域内CBF下降。然而，当受试者给出正确答案时，几乎所有区域的CBF都下降了。因此，出现了这样的问题：思维任务是否总是与r-CBF和/或CMRO2的增加相关？
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