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[儿童横纹肌肉瘤联合治疗的结果]

[Results of combined therapy in rhabdomyosarcoma in children].

作者信息

Lobo F, Vargas G, Camacho A, Jiménez E, Jiménez R, Carrillo J

出版信息

Bol Med Hosp Infant Mex. 1979 Mar-Apr;36(2):337-46.

PMID:758202
Abstract

In a study of rhabdomyosarcoma in children, 16 cases were treated and followed since 1971. Eight patients were staged I and II A and presented a mean survival time of 52 and 21 months respectively, whereas the remaining 8 patients were staged II B and III with a mean survival time of 20 and 9 months respectively. Of the 16 patients treated, 10 (62.5%) continue survival with an overall median survival time of 25 months. It is suggested that an early diagnosis and combined treatment including surgery, radiotherapy and chemotherapy with vincristine, cyclophosphamide and actinomicin and possibly adriamycin as a fourth drug, will give patients in underdeveloped countries, similar survivals and relief as those observed in developed countries. It is apparent that a multidisciplinary medical team is more important than the magnitud of economical resources.

摘要

在一项关于儿童横纹肌肉瘤的研究中,自1971年起对16例患者进行了治疗和随访。8例患者为I期和II A期,平均生存时间分别为52个月和21个月,而其余8例患者为II B期和III期,平均生存时间分别为20个月和9个月。在接受治疗的16例患者中,10例(62.5%)仍存活,总体中位生存时间为25个月。建议早期诊断并采用包括手术、放疗和化疗(使用长春新碱、环磷酰胺、放线菌素,可能还包括阿霉素作为第四种药物)的联合治疗,这将使欠发达国家的患者获得与发达国家患者相似的生存率和缓解情况。显然,多学科医疗团队比经济资源的规模更为重要。

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