Riordan F A, Thomson A P, Sills J A, Hart C A
Institute of Child Health, University of Liverpool, UK.
J Accid Emerg Med. 1995 Jun;12(2):126-9. doi: 10.1136/emj.12.2.126.
Children with bacterial meningitis often have a full blood count (FBC) measured urgently on admission. We investigated whether urgent FBC gave results that aided immediate management or predicted outcome in children with meningitis. FBCs were measured on admission during 190 episodes of bacterial meningitis in children admitted between 1984 and 1991. Significant anaemia was found in seven children, but immediate transfusion was only necessary in the three subjects who were in the Paediatric Intensive Care Unit (PICU). A white blood count of less than 5 x 10(9) L-1 was significantly associated with death (P < 0.02), but a Glasgow Coma Score of less than 8 predicted death more accurately (positive predictive value of 40%). FBC yielded immediately useful information only in the 15% of children who were admitted to PICU. Conscious level was a better predictor of outcome than FBC. We recommend that urgent FBC should be performed in children with meningitis admitted to a PICU; in other children with meningitis FBC can be analysed during normal laboratory hours.
患有细菌性脑膜炎的儿童入院时通常会紧急进行全血细胞计数(FBC)检查。我们研究了紧急FBC检查结果是否有助于对脑膜炎患儿进行即时治疗或预测其预后。对1984年至1991年间收治的190例患细菌性脑膜炎儿童入院时进行了FBC检查。发现7名儿童有明显贫血,但仅3名入住儿科重症监护病房(PICU)的患儿需要立即输血。白细胞计数低于5×10⁹/L与死亡显著相关(P<0.02),但格拉斯哥昏迷评分低于8分对死亡的预测更准确(阳性预测值为40%)。FBC仅在15%入住PICU的儿童中能立即提供有用信息。意识水平比FBC更能预测预后。我们建议,入住PICU的脑膜炎患儿应进行紧急FBC检查;其他脑膜炎患儿可在正常实验室工作时间进行FBC分析。