Lindvall O
Department of Neurology, University Hospital, Lund, Sweden.
Cell Transplant. 1995 Jul-Aug;4(4):393-400. doi: 10.1177/096368979500400410.
Cell transplantation is now being explored as a new therapeutic strategy to restore function in the diseased human central nervous system. Neural grafts show long-term survival and function in patients with Parkinson's disease but the symptomatic relief needs to be increased. Cell transplantation seems justified in patients with Huntington's disease and, at a later stage, possibly also in demyelinating disorders. The further development in this research field will require systematic studies in animal experiments but also well-designed clinical trials in small groups of patients.
细胞移植目前正作为一种新的治疗策略进行探索,以恢复患病人类中枢神经系统的功能。神经移植在帕金森病患者中显示出长期存活和功能,但症状缓解程度仍需提高。细胞移植对于亨廷顿病患者似乎是合理的,在后期,可能对脱髓鞘疾病患者也是如此。这一研究领域的进一步发展将需要在动物实验中进行系统研究,也需要在一小群患者中开展精心设计的临床试验。