Nørregaard J, Bülow P M, Vestergaard-Poulsen P, Thomsen C, Danneskiold-Samøe B
Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark.
Br J Rheumatol. 1995 Oct;34(10):925-31. doi: 10.1093/rheumatology/34.10.925.
The objectives were to determine whether the low muscle strength in fibromyalgia is due to lack of exertion and to determine the relation between strength and muscle area. Secondarily we examined the voluntary muscle strength of the different muscles of the leg. The twitch interpolation technique was used to estimate the degree of central activation and the 'true' quadriceps muscle strength. Muscle cross-sectional area was determined with magnetic resonance imaging (MRI). The estimated 'true' muscle strength was 91 Nm (S.D. = 34 Nm) in 15 fibromyalgia patients compared with 125 Nm (28 Nm) in 14 healthy controls (P < 0.02). The 'true' strength divided by the sum of the maximal areas of the four bellies of the quadriceps muscle was lower, being 1.56 Nm/cm2 (0.32 Nm/cm2) in fibromyalgia patients compared with 2.11 Nm/cm2 (0.39 Nm/cm2) in the controls (P < 0.001). The voluntary muscle strength of the flexor muscles of the knee and of the plantar flexors of the ankle was markedly reduced in patients, but no significant differences could be observed in the strength of the dorsal flexors of the ankle. In conclusion, a reduction of the estimated 'true' quadriceps muscle strength per unit area of about 35% was found in fibromyalgia patients.
本研究目的是确定纤维肌痛患者肌肉力量低是否归因于缺乏运动，并确定力量与肌肉面积之间的关系。其次，我们检查了腿部不同肌肉的随意肌力量。采用抽搐插值技术来估计中枢激活程度和“真实”股四头肌力量。通过磁共振成像（MRI）测定肌肉横截面积。15名纤维肌痛患者的估计“真实”肌肉力量为91 Nm（标准差 = 34 Nm），而14名健康对照者为125 Nm（28 Nm）（P < 0.02）。纤维肌痛患者的“真实”力量除以股四头肌四个肌腹最大面积之和较低，分别为1.56 Nm/cm²（0.32 Nm/cm²）和2.11 Nm/cm²（0.39 Nm/cm²）（P < 0.001）。患者膝关节屈肌和踝关节跖屈肌的随意肌力量明显降低，但踝关节背屈肌力量未观察到显著差异。总之，纤维肌痛患者股四头肌每单位面积的估计“真实”力量降低了约35%。
