逆转录病毒介导的MHC II类cDNA转入猪骨髓细胞 - Suppr

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超能文献

Retrovirus-mediated transfer of MHC class II cDNA into swine bone marrow cells.

作者信息

LeGuern C, Shimada H, Emery D W, Germana S, Shafer G E, Sachs D H

机构信息

Transplantation Biology Research Center, Massachusetts General Hospital, Boston 02129, USA.

出版信息

J Mol Med (Berl). 1995 Jun;73(6):269-78. doi: 10.1007/BF00231613.

DOI:10.1007/BF00231613

PMID:7583449

Abstract

摘要

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Retrovirus-mediated transfer of MHC class II cDNA into swine bone marrow cells.逆转录病毒介导的MHC II类cDNA转入猪骨髓细胞

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Expression of an allogeneic MHC DRB transgene, through retroviral transduction of bone marrow, induces specific reduction of alloreactivity.通过逆转录病毒转导骨髓表达同种异体MHC DRB转基因，可诱导同种异体反应性特异性降低。

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Expression of allogeneic class II cDNA in swine peripheral blood mononuclear cells following retroviral-mediated gene transfer into bone marrow.逆转录病毒介导的基因转移至骨髓后猪外周血单个核细胞中同种异体II类cDNA的表达

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本文引用的文献

Culture and characterization of hematopoietic progenitor cells from miniature swine.小型猪造血祖细胞的培养与鉴定

Exp Hematol. 1996 Jul;24(8):927-35.

The biochemistry and cell biology of antigen processing and presentation.抗原加工与呈递的生物化学和细胞生物学

Annu Rev Immunol. 1993;11:403-50. doi: 10.1146/annurev.iy.11.040193.002155.

Regression of bladder tumors in mice treated with interleukin 2 gene-modified tumor cells.用白细胞介素2基因修饰的肿瘤细胞治疗的小鼠膀胱肿瘤的消退

J Exp Med. 1993 Apr 1;177(4):1127-34. doi: 10.1084/jem.177.4.1127.

Retrovirus-mediated transfer and expression of an allogeneic major histocompatibility complex class II DRB cDNA in swine bone marrow cultures.逆转录病毒介导的同种异体主要组织相容性复合体II类DRB cDNA在猪骨髓培养物中的转移与表达。

Blood. 1993 May 1;81(9):2460-5.

Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.基因导入造血干细胞：无需骨髓消融即可长期维持体外活化祖细胞

Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):350-4. doi: 10.1073/pnas.91.1.350.

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells.HLA - DMA和 - DMB基因对于抗原呈递细胞中MHC II类/肽复合物的形成都是必需的。

Nature. 1994 Apr 7;368(6471):554-8. doi: 10.1038/368554a0.

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules.HLA-DM在II类主要组织相容性分子的抗原呈递中起关键作用。

Nature. 1994 Apr 7;368(6471):551-4. doi: 10.1038/368551a0.

Induction of specific tolerance to MHC-disparate allografts through genetic engineering.通过基因工程诱导对主要组织相容性复合体（MHC）不相合同种异体移植物的特异性耐受。

Exp Nephrol. 1993 Mar-Apr;1(2):128-33.

Assembly, transport, and function of MHC class II molecules.MHC II类分子的组装、运输及功能

Annu Rev Immunol. 1994;12:259-93. doi: 10.1146/annurev.iy.12.040194.001355.

The pig as a potential xenograft donor.猪作为潜在的异种移植供体。

Vet Immunol Immunopathol. 1994 Oct;43(1-3):185-91. doi: 10.1016/0165-2427(94)90135-x.

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