Dallman P R, Siimes M A
J Pediatr. 1979 Jan;94(1):26-31. doi: 10.1016/s0022-3476(79)80344-3.
Percentile curves were calculated for hemoglobin and mean corpuscular volume in children between 0.5 and 16 years of age. The curves were derived from several populations of non-indigent white children who lived near sea level. Subjects were excluded from the reference population if they had laboratory evidence of iron deficiency, thalassemia minor, and/or hemoglobinopathy. The final reference populations included 9,946 children for the derivation of the hemoglobin curves and 2,314 for the MCV curves. The percentile curves should be particularly applicable to the diagnosis and screening of iron deficiency and thalassemia minor.
计算了0.5至16岁儿童血红蛋白和平均红细胞体积的百分位数曲线。这些曲线源自居住在海平面附近的几个非贫困白人儿童群体。如果受试者有缺铁、轻度地中海贫血和/或血红蛋白病的实验室证据,则被排除在参考人群之外。最终的参考人群包括用于推导血红蛋白曲线的9946名儿童和用于推导平均红细胞体积曲线的2314名儿童。百分位数曲线应特别适用于缺铁和轻度地中海贫血的诊断和筛查。